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Mankin scoring system of cartilage degeneration.
| Grade | Grade | ||||
|---|---|---|---|---|---|
| I | Structure | III | Safranin-O Staining | ||
| Normal | 0 | Normal | 0 | ||
| Surface irregularities | 1 | Slight reduction | 1 | ||
| Pannus and surface irregularities | 2 | Moderate reduction | 2 | ||
| Clefts to transitional zone | 3 | Severe reduction | 3 | ||
| Clefts to radial zone | 4 | No dye noted | 4 | ||
| Clefts to calcified zone | 5 | ||||
| Complete disorganization | 6 | ||||
| II | Cells | IV | Tidemark Integrity | ||
| Normal | 0 | Intact | 1 | ||
| Diffuse hypercellularity | 1 | Crossed by blood vessels | 2 | ||
| Cloning | 2 | ||||
| Hypocellularity | 3 |
