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. 2011 Mar;162(6):1364–1379. doi: 10.1111/j.1476-5381.2010.01143.x

Figure 4.

Figure 4

Addition of 12(S)-HETE or 12(S)-HPETE did not affect baicalein-induced long-term potentiation (LTP) enhancement. (A) Pre-incubation of slices with 12(S)-HETE (250 nM) did not affect the induction of high-frequency stimulation (HFS)-induced LTP and baicalein-facilitated LTP. (B) Summary data of the average field excitatory postsynaptic potential (fEPSP) slope after HFS relative to untreated, baicalein, 12(S)-HETE, the combination of 12(S)-HETE and baicalein. (C) 12(S)-HPETE did not block HFS-induced LTP and baicalein-facilitated LTP. (D) Summary data of the average fEPSP slope after HFS relative to untreated, baicalein, 12(S)-HPETE, the combination of 12(S)-HPETE and baicalein. The superimposed fEPSP in the top portion showed respective recordings from representative experiments taken at the time indicated by the number. Each point was the normalized mean ± SEM of six slices.