Table 3.

Morphological evaluation of glomerular size, glomerular sclerosis and tubulointerstitial damage at the end of study (58 weeks of age)

	LETO	OLETF-CON	OLETF-SIL
Glomerular size (µm2)	9207.80 ± 199.18	10 856.60 ± 206.65*	9921.71 ± 266.60#
Glomerular sclerosis score (0–4)	0.12 ± 0.02	1.42 ± 0.13*	0.89 ± 0.13#
Tubulointerstitial damage score (0–5)	0	0.43 ± 0.19*	0.29 ± 0.17

Morphometric analysis of kidney sections from the LETO rats, OLETF-CON rats and OLETF-SIL rats.

Data are mean ± SEM.

^*P < 0.001 vs. LETO rats.

^#P < 0.05 vs. OLETF-CON rats.

LETO, Long-Evans Tokushima Otsuka; OLETF, Otsuka Long-Evans Tokushima Fatty.