FIGURE 7. The contractile detrusor response to direct electrical stimulation of the DNP was present following acute SCI.
The intravesical pressure responses to 20 second trains of stimulation at 33 Hz, 200μA before SCT (A) and 15 hours after SCT at T10 (B) in one cat. (C) The percent of trials that elicited detrusor contractions at different frequencies shows that detrusor contraction was dependent on stimulation frequency (p<0.0001, Kruskal-Wallis test, n=75 trials across 2 cats). Stimulation at 20, 33, and 40 Hz elicited contractions significantly more frequently than stimulation at 2, 5, and 10 Hz (*p<0.05, Bonferroni inequalities). Stimulation at 2, 5, or 10 Hz did not elicit any detrusor contractions following SCT.