Table 1.

Comparison of risk factors associated with HIV seroconversion among 1927 initially HIV-negative spouses in Zhumadian city

Characteristic of the initially HIV- negative partner	Did not seroconvert	Seroconverted	Univariate RR (95% CI)	Multivariate RR (95% CI)
Demographic characteristics
Sex
Male	1043	49	0.91(0.59–1.41)
Female	800	35	1.00
Age (years)
<45	1132	45	1.00
≥ 45	711	39	1.26(0.82–1.94)
High-risk behaviors
Sexual Intercourse in past 3 months
Yes	1535	76	1.90(0.91–3.93)
No	308	8	1.00
Frequency of sex in past month
<4	720	15	1.00	1.00
≥4	805	61	5.13(2.76–9.53)	5.24(2.55–10.77)
Always used condoms in the past month
Yes	1460	42	1.00	1.00
No	75	34	12.64(8.18–19.57)	8.42(4.83–14.67)
Extra-marital sex
Yes	6	1	3.22(0.45–23.14)
No	1828	83	1.00
No Response	9	0
Medical history of index spouses
AIDS diagnosis among those with HIV infection
Yes	1583	73	1.00(0.53–1.89)
No	260	11	1.00
ART
Yes	1303	66	1.32(0.78–2.22)
No	540	18	1.00
Switched ART regimen
Yes	260	6	1.00	1.00
No	1043	60	2.66(1.15–6.15)	1.99(0.85–4.65)
Last recorded CD4 of index spouse (cells/μL)
0–199	17	416	1.00
200–349	21	421	1.20(0.64–2.28)
≥350	36	639	1.39(0.78–2.48)
Quality of Life Score (points)
Physical domain
<12	357	22	1.67(1.03–2.72)	0.95(0.47–1.94)
≥12	1486	62	1.00	1.00
Psychological domain
<12	447	32	2.27(1.46–3.54)	2.33(1.21–4.48)
≥12	1396	52	1.00	1.00
Social domain
<12	202	12	1.72(0.93–3.17)
≥12	1641	72	1.00
Environment domain
<12	490	27	1.58(0.997–2.50)
≥12	1353	57	1.00