Table 3.
Number of BrdU-labeled cells per mm2 of periosteum (mean ± SD)
| Fibrous layer | Inner (‘osteogenic’) layer | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Region* | 2 weeks† | 4 weeks† | 6 weeks† | Combined† | 2 weeks† | 4 weeks† | 6 weeks† | Combined† | |
| Appositional | |||||||||
| Mandible | R(CBC) | 86 ± 69 | 105 ± 126 | 74 ± 46 | 88 ± 77 | 1051 ± 307 | 852 ± 452 | 2144 ± 116 | 1349 ± 664 |
| R(CBA) | 61 ± 25 | 67 ± 43 | 64 ± 42 | 64 ± 32 | 651 ± 101 | 665 ± 174 | 1665 ± 681 | 993 ± 616 | |
| R(DB) | 164 ± 39 | 418 ± 31‡ | 102 ± 82 | 204 ± 144 | 462 ± 259 | 1760 ± 897‡ | 675 ± 268 | 866 ± 684 | |
| R(RB) | 68 ± 87‡ | – | – | 68 ± 87 | 82 ± 18‡ | – | – | 82 ± 18 | |
| R(VB) | 118 ± 87 | 215 ± 108 | 59 ± 20 | 131 ± 98 | 381 ± 211 | 814 ± 362 | 1078 ± 307 | 788 ± 400 | |
| R(MFL) | 137 ± 105 | 162 ± 145 | 125 ± 10 | 141 ± 91 | 270 ± 28 | 326 ± 116 | 844 ± 458 | 480 ± 362 | |
| R(ML) | 137 ± 42 | 260 ± 33 | 121 ± 36 | 173 ± 73 | 327 ± 73 | 633 ± 224 | 643 ± 94 | 535 ± 201 | |
| Palate | P(O) | 300 ± 123 | 231 ± 85 | 91 ± 51 | 207 ± 122 | 412 ± 103 | 476 ± 204 | 302 ± 92 | 396 ± 145 |
| P(CB) | 136§ | 323 ± 205 | 40 ± 2‡ | 198 ± 192 | 110§ | 626 ± 145 | 178 ± 249‡ | 473 ± 228 | |
| Arch | A(DB) | 63 ± 48 | 277 ± 354 | 38 ± 37 | 126 ± 213 | 591 ± 161 | 1165 ± 282 | 612 ± 144 | 789 ± 333 |
| A(VB) | 39 ± 14 | 237 ± 228 | 21 ± 3 | 99 ± 154 | 129 ± 63 | 655 ± 563 | 533 ± 103 | 445 ± 376 | |
| Z(L) | 252 ± 112 | 194 ± 205 | 27 ± 11 | 157 ± 154 | 498 ± 149 | 749 ± 263 | 359 ± 149 | 535 ± 240 | |
| Z(M) | 470§ | 205 ± 133 | 57 ± 44 | 179 ± 169 | 308§ | 541 ± 159 | 214 ± 136 | 367 ± 205 | |
| Fl(L) | 142 ± 30 | 257 ± 218 | 13 ± 2 | 137 ± 152 | 300 ± 33 | 618 ± 111 | 457 ± 250 | 458 ± 195 | |
| Fl(M) | 215 ± 171 | 459 ± 158 | 31 ± 44‡ | 260 ± 220 | 362 ± 265 | 616 ± 327 | 174 ± 3‡ | 410 ± 293 | |
| T(L) | 109 ± 92 | 184 ± 135 | 15 ± 10 | 107 ± 116 | 488 ± 113 | 624 ± 117 | 1010 ± 73 | 724 ± 243 | |
| All appositional | 146 ± 55¶ | 606 ± 301¶,** | |||||||
| Resorptive | |||||||||
| Mandible | R(DB) | 84 ± 36‡ | 117 ± 54‡ | 79§ | 96 ± 38 | 390 ± 256‡ | 266 ± 86‡ | 196§ | 301 ± 160 |
| R(RB) | 116 ± 60‡ | – | 97 ± 65‡ | 106 ± 52 | 414 ± 367‡ | – | 570 ± 655 | 492 ± 443 | |
| R(MFM) | 257 ± 28 | 306 ± 348 | 206 ± 47 | 257 ± 182 | 308 ± 167 | 211 ± 138 | 354 ± 157 | 291 ± 148 | |
| R(ML) | 197 ± 44 | 349 ± 77 | 163 ± 65 | 236 ± 102 | 320 ± 97 | 521 ± 201 | 257 ± 61 | 366 ± 166 | |
| Palate | P(N) | 227 ± 44 | 332 ± 102 | 117 ± 57 | 226 ± 112 | 216 ± 18 | 445 ± 187 | 296 ± 111 | 319 ± 149 |
| Arch | Z(M) | 76 ± 40‡ | 87§ | 38 ± 5‡ | 63 ± 31 | 93 ± 90‡ | 434§ | 268 ± 2‡ | 253 ± 129 |
| Fl(M) | 75 ± 78 | 233 ± 69 | 21 ± 18 | 110 ± 109 | 99 ± 75 | 850 ± 439 | 137 ± 69 | 362 ± 430 | |
| T(M) | 258 ± 168 | 311 ± 364 | 39 ± 22 | 202 ± 236 | 201 ± 97 | 403 ± 20 | 142 ± 53 | 249 ± 137 | |
| All resorptive | 162 ± 76¶ | 329 ± 79¶,** | |||||||
For region abbreviations, see Table 1.
n = 3 pigs per age group and nine pigs combined except where specified. Sample size varied because of individual differences in the regional occurrence of modeling activity.
n = 2.
n = 1.
Difference between fibrous and inner layers, P < 0.005.
Difference between appositional and resorptive, P = 0.02.