Table 2.
Genetic Locus* | df† | N | P-value§ |
---|---|---|---|
NOS1 | 7 | 2701 | 0.79 |
NOS2A | 4 | 2611 | 0.0002 |
NOS3 | 6 | 2720 | 0.79 |
ARG1 | 2 | 2742 | 0.67 |
ARG2 | 3 | 2735 | 0.01 |
For details of SNPs included within each locus/haplotype block, see Tables S1 through S4 in the Supporting information.
Degrees of freedom (df) reflect the number of principal components that accounted for ≥80% of the locus variance.
Global P-values are from likelihood ratio tests based on the degrees of freedom presented. All models include adjustment for covariates listed in the ‘Methods’ section.