Table 1.
List of blood group genes, transcripts, clinically relevant antigens, and nucleotide polymorphisms.
| ISBT Name (Symbol No.) |
Reference Seq Gene (mRNA) |
Common Antigens |
Nucleotide polymorphism (dbSNP) |
|---|---|---|---|
| ABO (ABO 001) |
NG_006669.1 (NM_020469.2) |
A1>A2 A>B A>O |
nt1061ΔC (rs56392308) nt526C>G (rs7853989) nt703G>A (rs8176743) nt796C>A (rs8176746) nt803G>C (rs8176747) nt261G/ΔG (rs8176719) |
| MNS (MNS 002) |
NG_007470.2 (NM_002099.4) NG_007483.1 (NM_002100.3) |
M>N S>s |
nt59C>T;71G>A;72T>G (rs7682260;7687256;7658293) nt143T>C (rs7683365) |
| Rh (RH 004) |
NG_007494.1 (NM_016124.3) NG_009208.1 (NM_020485.3) |
D C>c E>e |
(multiple targets) nt307T>C (rs676785) nt676C>G (rs609320) |
| Lutheran (LU 005) |
NG_007480.1 (NM_005581.3) |
Lua > Lub | nt230A>G (rs28399653) |
| Kell (KEL 006) |
NG_007492.1 (NM_000420.2) |
K>k Kpa>Kpb Jsa>Jsb |
nt578T>C (rs8176058) nt841T>C (rs8176059) nt1790C>T (rs8176038) |
| Duffy (FY 008) |
NG_011626.1 (NM_002036.2) |
Fya>Fyb Fyb>Fyx Fynull |
nt125G>A (rs12075) nt265C>T (rs34599082) nt-67t>c (rs2814778) |
| Kidd (JK 009) |
NG_011775.1 (NM_015865.4) |
Jka>Jkb | nt838G>A (rs1058396) |
| Diego (DI 010) |
NG_007498.1 (NM_000342.3) |
Dia>Dib | nt2561T>C (rs2285644) |
| Yt (YT 011) |
NG_007474.1 (NM_015831.2) |
Yta>Ytb | nt1057C>A (rs1799805) |
| Scianna (SC 013) |
NG_008749.1 (NM_018538.3) |
Sc1>Sc2 | nt169G>A (rs56025238) |
| Dombrock (DO 014) |
NG_007477.1 (NM_021071.2) |
Doa>Dob Hy Jo |
nt793A>G (rs11276) nt323G>T (rs28362797) nt350C>T (rs28362798) |
| Colton (CO 015) |
NG_007475.1 (NM_198098.1) |
Coa>Cob | nt134C>T (rs28362692) |
| Cromer (CR 021) |
NG_007465.1 (NM_000574.3) |
Cr(a+)>Cr(a− ) |
nt679G>C (rs60822373) |
| Knops (KN 022) |
NG_007481.1 (NM_000573.3) |
Kna>Knb McCa>McCb Sla>Vil |
nt4681G>A (rs41274768) nt4768A>G (rs17047660) nt4801A>G (rs17047661) |