Table 2.

Patient Demographics and Clinical Characteristics

Characteristic	Observation (n = 179)		WBRT (n = 180)		Total (N = 359)
	No. of Patients	%	No. of Patients	%	No. of Patients	%
Age, years
Median	61		60		60
Range	37-80		26-81		26-81
Sex
Male	122	68	113	63	235	65
Female	57	32	67	37	124	35
WHO performance status
0	82	46	75	42	157	44
1	78	44	84	47	162	45
2	19	11	21	12	40	11
Neurologic status
No deficit	97	54	97	54	194	54
Some deficit, useful work	52	29	54	30	106	30
Moderate impairment	29	16	29	16	58	16
Major impairment	1	1	0	0	1	0
Localization of primary tumor
Lung (NSCLC)	93	52	97	54	190	53
Breast	20	11	22	12	42	12
Kidney	13	7	16	9	29	8
Colorectal	16	9	14	8	30	8
Melanoma	8	5	10	6	18	5
Other	15	8	12	7	27	8
CUP	14	8	9	5	23	6
Macroscopic tumor outside the brain
Absent	89	50	79	44	168	47
Present	82	46	91	51	173	48
Unknown	8	4	10	6	18	5

Abbreviations: WBRT, whole-brain radiotherapy; NSCLC, non–small-cell lung cancer; CUP, cancer of unknown primary tumor.