Table 5.
Intracranial Progression and Salvage Therapy
| Progression and Salvage Therapy | Observation |
WBRT |
||||
|---|---|---|---|---|---|---|
| No. of Patients | % of Patients Who Experienced Progression (n = 139) | % of Total Patients (n = 179) | No. of Patients | % of Patients Who Experienced Progression (n = 87) | % of Total Patients (n = 180) | |
| Site of intracranial progression | ||||||
| New sites | 60 | 43 | 34 | 44 | 51 | 24 |
| Initial sites | 54 | 39 | 30 | 31 | 36 | 17 |
| Both | 19 | 14 | 11 | 7 | 8 | 4 |
| Unknown | 6 | 4 | 3 | 5 | 6 | 3 |
| Salvage treatment | ||||||
| WBRT | 56 | 40 | 31 | 6 | 7 | 3 |
| Radiosurgery | 21 | 15 | 12 | 20 | 23 | 11 |
| Surgery | 11 | 8 | 6 | 3 | 3 | 2 |
| Radiosurgery + WBRT | 1 | 1 | 1 | |||
| Surgery + WBRT | 3 | 2 | 2 | |||
Abbreviation: WBRT, whole-brain radiotherapy.