Fig. 1. Electron microscopy of CCT–β-tubulin complexes. (A) A gallery of top views obtained by negative staining (NS) or cryoelectron microscopy (CR). (B) Two-dimensional average of CCT–β-tubulin shown as contour lines (average of 2313 particles). (C) A view of three-dimensional reconstructions of the CCT–β-tubulin complexes obtained from stained specimens. Approximately 40 Å of the height of the CCT particle is reconstructed.