Fig. 2. Three-dimensional reconstructions of CCT and CCT–tubulin complexes. (A) Side view of the three-dimensional reconstruction obtained from substrate-free top views. (B) A cut along the longitudinal axis of tubulin-free CCT. (C–H) Views of the three-dimensional reconstruction obtained from top views of CCT–tubulin complexes: (C) side view; (D) a cut along the longitudinal axis of the CCT–tubulin complex; (E and F) views of the tubulin-free ring; (G and H) views of the tubulin-bound ring.