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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Chem Biol Drug Des. 2010 Oct 11;76(6):460–471. doi: 10.1111/j.1747-0285.2010.01037.x

Figure 10.

Figure 10

CPK models and molecular electrostatic potential (MEP) maps calculated for FPP (1b), dihydroazide 5b and alkyne 6b. Top: CPK models of (A) FPP (1b); (B) 5b; (C) 6b. Bottom: MEP for (D) FPP (1b); (E) 5b; (F) 6b. For clarity, only cabons distal to C-5 are shown. Carbons 1–4 and the diphosphate groups are not shown since these are the same in all structures. For CPK models, the following colors were used: Carbon (grey), Hydrogen (white), Nitrogen (blue) and Oxygen (red). For MEP maps, potentials were plotted on a surface of constant density (density = 0.02). Electronegative areas are shown in red and electropositive areas are shown in blue.