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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Nov 12;35(2):218–228. doi: 10.1111/j.1530-0277.2010.01337.x

Table 5. Family History Effects: Foci of Maximally Activated Brain Regions.

Talairach Coordinates
Region BA x y z Cluster SPM {t}
FH+: Interference – Color Naming
L. Middle Frontal Gyrus 6 -35 1 38 342 5.29*
L. Insula -40 12 17 440 4.50*
R. Anterior Cingulate Gyrus 32 14 29 20 74 4.37
L. Medial Frontal Gyrus 6 -18 9 48 35 3.90
L. Medial Frontal Gyrus 9 -20 28 25 38 3.90
R. Middle Frontal Gyrus 8 28 15 40 45 3.59
L. Insula -36 16 -2 21 3.57

FH-: Interference – Color Naming
L. Precentral Gyrus 6 -38 -1 32 43 3.32

L, left hemisphere; R, right hemisphere. BA, Brodmann Area. MNI coordinates transformed into Talairach Space, x=center/left of midline, y=anterior/posterior to anterior commissure, z=superior/inferior to horizontal plane through AC-PC line. SPM {t} scores significant beyond p<.001 (uncorrected) for ROI analyses are reported.

*

Indicates significance at small volume corrected threshold, p<.05.