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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Nov 12;35(2):218–228. doi: 10.1111/j.1530-0277.2010.01337.x

Table 7. Family History Density: Regression with Brain Activation.

Talairach Coordinates
Region BA x y z Cluster SPM {t}
Positive Regression: FHD and Interference – Color Naming
R. Middle Frontal Gyrus 8 26 11 44 1108 6.64*
L. Superior Frontal Gyrus 6 -13 15 49 198 4.83
L. Cingulate Gyrus 24 -12 11 30 59 4.60
R. Precentral Gyrus 6 39 -7 35 98 4.55
L. Insula -38 16 14 255 4.48*
L. Middle Frontal Gyrus 9 -29 32 27 456 4.14

Negative Regression: FHD and Interference – Color Naming
L. Superior Frontal Gyrus 6 -6 -6 67 223 5.55
L. Precentral Gyrus 6 -24 -13 64 29 4.75
R. Medial Frontal Gyrus 6 6 -27 65 47 3.54

L, left hemisphere; R, right hemisphere. BA, Brodmann Area. MNI coordinates transformed into Talairach Space, x=center/left of midline, y=anterior/posterior to anterior commissure, z=superior/inferior to horizontal plane through AC-PC line. SPM {t} scores significant beyond p<.001 (uncorrected) for ROI analyses are reported.

*

Indicates significance at small volume corrected threshold, p<.05.