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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: J Immunol. 2010 Dec 6;186(1):242–254. doi: 10.4049/jimmunol.1000494

FIGURE 6.

FIGURE 6

Relative contribution of αvβ3 and ICAM-1 to time-dependent adhesion of Lu1205 cells to PMNs in the absence of fibrin(ogen) (A), presence of fibrinogen (B), or fibrin (C-E) under 62.5 s-1 shear rate. Lu1205 cells were pre-treated with anti-ICAM-1, αvβ3 and/or CD11a mAb (A-C) or siRNA targeting ICAM-1 or αvβ3 (D-E) before being sheared with PMNs. Fibrin was made from 0.053 U/ml thrombin, 1.5 mg/ml Fg and 4 mM GPRP; Fibrinogen stands for 1.5 mg/ml fibrinogen solution. Values are means ± SEM from three independent experiments.