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. Author manuscript; available in PMC: 2011 Jun 2.
Published in final edited form as: Nature. 2010 Dec 2;468(7324):701–704. doi: 10.1038/nature09595

Figure 2. Lkb1 ablation results in reduced HSC reserves and decreased repopulating potential.

Figure 2

a, b, The numbers of LSK cells (a) and LT-HSCs (b) at various DPIs in Lkb1 WT and KO bone marrows. c, The relative fold changes (Lkb1 KO/WT) of the percentages of BrdU+ cells from various hematopoietic cell lineages in Lkb1 WT and KO bone marrows at 1 DPI. n = or > 3 at each time point (a–c). d, The percentages of donor-derived cells in peripheral blood by CD45 staining in 1:1 competitive transplantation. n = 15. *: P > 0.4; **: P < 0.01.