Live cells are gated based on 7AAD staining and Forward Scatter (FSC) vs Side Scatter (SSC) plot (A and D) and singlets are plotted (B and E). The gated side population cells are displayed in a double scatter plot between Red 650 nm and Blue (450/40 nm) emission (C). ABCG2 mediated DCV efflux is inhibited in the presence of FTC (D-F). The side population profile of the specimen used in this experiment is 0.9% (C) which is inhibited in the presence of FTC (F).
FSC – Forward Scatter
SSC – Side Scatter
FSC-H – Forward Scatter Height
FSC-W – Forward Scatter Width
SP – Side Population
NSP – Non-side Population