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. Author manuscript; available in PMC: 2011 Dec 15.
Published in final edited form as: J Immunol. 2010 Nov 12;185(12):7681–7690. doi: 10.4049/jimmunol.1002803

FIGURE 1.

FIGURE 1

MC-deficient mice are protected against epidermal scald injury at 54 °C. The clinical response to an epidermal scald of 25 seconds duration in MC-sufficient WBB6F1-+/+ (WT) mice and MC-deficient WWv mice was compared at 3 different temperatures at 3 and 13 d after injury. Pictures show the 2 mice in each group. Hair regrowth at the scald site of the 54 °C treated WWv mice is not seen due to its lack of pigment. The black marks were replaced each day to define the residual injury and do not represent the area of the original scald site. Protection against a visible burn in MC-deficient mice exposed to a 54 °C scald for 25 s was confirmed in 2 further experiments with sufficient and deficient strains with 5 mice per group.