Table I. Sequence context of acetylatable lysines in histones H3 and H4 from S.cerevisiae.
Histone | Acetylatable lysine | Sequence |
---|---|---|
H3 | 9 | RKSTG |
H3 | 14 | GKAPR |
H3 | 18 | RKQLA |
H3 | 23 | SKAAR |
H4 | 5 | GKGGK |
H4 | 8 | GKGLG |
H4 | 12 | GKGGA |
H4 | 16 | AKRHR |
The table shows the sequences from K – 1 to K + 3, where K is the acetylatable lysine. Residues that could potentially make secondary interactions with the Gcn5p bromodomain are shown in bold.