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. Author manuscript; available in PMC: 2011 Jul 13.
Published in final edited form as: Nature. 2010 Dec 15;469(7329):250–254. doi: 10.1038/nature09604

Figure 1. ATM and XLF have redundant functions in lymphocyte development.

Figure 1

(A) Representative flow cytometric analyses of bone marrow, spleen and thymus from WT, XLFΔ/Δ, ATM−/−, Rag2−/−, XLFΔ/ΔATM−/− and XLFΔ/ΔATM−/−HL mice (see Method for further description of mouse lines). Numbers on the plot are percentage of total cells represented by indicated population. (B) Total thymocyte, DP thymocyte and (C) IgM+ splenic B cell numbers. Each value listed represents the average ± standard deviation from at least three mice between 4 to 12 weeks of age. Details are found in Supp. Tab.1.