. Author manuscript; available in PMC: 2011 Jul 13.

Published in final edited form as: Nature. 2010 Dec 15;469(7329):250–254. doi: 10.1038/nature09604

Table 1. H2AX and XLF have redundant functions in murine embryonic development.

The Indicated genotypes were obtained by inter-crossing H2AX^+/−XLF^Δ/Δ mice as described⁵,¹²,²². H2AX-deficiency does not cause embryonic lethality ²²,²⁷.

	H2AX+/+ XLFΔ/Δ	H2AX+/− XLFΔ/Δ	H2AX−/−XLFΔ/Δ	Absorbed	Total
Birth	14	46	0		60
Birth (exp)	15	30	15
E13.5	8	28	0	8	44
E13.5(exp)	11	22	11