Figure 1.

More robust B-cell repopulation by Id1^G/G bone marrow. Bone marrow transplant was performed by injecting 5×10⁵ whole bone marrow cells from WT or Id1^G/G mice into sublethally irradiated CD45.1⁺ congenic recipients as diagrammed. On days 10 and 14 post-transplant, donor-derived cells were identified by their CD45.2 surface marker and CD19⁺ and Mac-1⁺ cells were enumerated. The bar graph shows the average numbers of donor-derived CD19⁺ or Mac-1⁺ cells per femur with SEM (n>6). Statistical values as indicated were obtained using student's t-test. WT, wild type.