Table 2.
Glycemic Parameters
| Total (748) |
Survivor (713) |
Nonsurvivor (35) |
P-value | Diabetes (270) |
No Diabetes (478) |
P-value | 2005 (365) |
2006 (383) |
P-value | |
|---|---|---|---|---|---|---|---|---|---|---|
| TWMG (mg/dl) | 137 (44.7) | 138 (45.1) | 128 (33.1) | 0.19 | 151.5 (53.1) | 129.3 (36.8) | <0.0001 | 142 (47) | 133 (42) | 0.004 |
| 3-day TWMG (mg/dl) | 142.0 (51.3) | 142 (51.5) | 130 (44.6) | 0.15 | 157.0 (60.0) | 133.2 (43.3) | <0.0001 | 145.9 (53.9) | 137.9 (48.3) | 0.03 |
| *GLI (mg/dl)2/hr*day−1 | 7.15 (2.39-19.1) |
6.82 (2.29-18.4) |
18.1 (8.76-44.2) |
0.0003 | 8.6 (3.25-23.1) |
6.0 (1.89-17.6) |
0.0009 | 34.4 (101) | 29.1 (105) | 0.48 |
| *SD | 3.88 (3.47-4.22) |
3.89 (3.49-4.24) |
3.76 (3.35-4.05) |
0.11 | 4.06 (3.73-4.36) |
3.78 (3.37-4.13) |
<0.0001 | 3.93 (3.56-4.29) |
3.83 (3.40-4.19) |
0.013 |
| *CV | 0.30 (0.23-0.39) |
0.30 (0.23-0.39) |
0.29 (0.21-0.36) |
0.61 | 0.34 (0.26-0.41) |
0.29 (0.21-0.38) |
<0.0001 | 0.31 (0.24-0.40) |
0.30 (0.22-0.38) |
0.18 |
| HbA1c (%, N=334) | 7.58 (1.96) | 7.61 (1.97) | 6.47 (1.03) | 0.13 | 8.40 (1.92) | 5.97 (0.48) | * | 7.71 (1.95) | 7.48 (1.97) | 0.29 |
| Hypoglycemia (% of patient-days) |
6.5 | 6.3 | 8.4 | 0.05 | 8.7 | 5.3 | 0.008 | 6.0 | 7.0 | 0.36 |
| Hypoglycemia (N, %) | 258 (34.2%) | 239 (33.5%) | 19 (54.3%) | 0.012 | 100 (37.0%) | 158 (33.1%) | 0. 30 | 124 (34.0%) | 134 (35.0%) | 0.82 |
| >70 mg/dl | 490 (65.5%) | 474 (66.5%) | 16 (45.7%) | |||||||
| 60-69 mg/dl | 90 (12.0%) | 82 (11.5%) | 8 (22.9%) | 0.07# | ||||||
| 40-59 mg/dl | 124 (16.6%) | 116 (16.3%) | 8 (22.9%) | |||||||
| <40 mg/dl | 44 (5.9%) | 41 (5.8%) | 3 (8.6%) |
*
Median (IQR), and analyzed using Wilcoxon rank sum. All other continuous variables reported as mean (SD) and analyzed with student’s t-test.
#
Pearson chi square test for overall association across 2 groups × 4 categories. TWMG=time-weighted mean glucose, GLI=time-adjusted glycemic lability index. Hypoglycemia is defined as any glucose <70 mg/dl except as indicated.