Skip to main content
. Author manuscript; available in PMC: 2011 Mar 16.
Published in final edited form as: Curr Hypertens Rev. 2010 Nov 1;6(4):266–281. doi: 10.2174/157340210793611668

Figure 10. Calpain-1 transcriptome, protein abundance, and activity increase in the aged aortic wall.

Figure 10

A. Average data of calpain-1 transcriptome. B. Western blots for calpain-1 protein of rat intact aortae (upper panel); average data (lower panel). C. Dual en face fluorescence staining for α-SMA (green) and calpain-1 (red) in the medial aortic sections from young (upper panels) and old rats (lower panels). Nuclei were counterstained with DAPI (blue). Merged image is depicted in right panel (yellow-blue). Magnification: X400. D. Western blot for calpain substrate α-II spectrin from aortic lysates (left panels). Average cleaved spectrin fraction (right panel). *p<0.05, old vs. young. From Jiang L et al [10].