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. Author manuscript; available in PMC: 2011 Mar 16.
Published in final edited form as: Nature. 2010 Jul 29;466(7306):642–646. doi: 10.1038/nature09190

Fig. 1. Novel class of sRNAs antisense to 3’ ends annotations.

Fig. 1

(A) Distribution of sRNA detected using tSMS using the no-amplification protocol and Illumina platforms2 on both strands of the genome within the FAU locus; (B) Distribution of distances between the 5’ ends of tSMS sequences obtained using the un-amplifed protocol and 3’ ends of annotations of the opposite strand. Base to the right of “0” represents the most 3’ base of an RNA, see Supplementary Information for additional explanation and details. (C) Schematic representation of a possible mode of generation of sRNAs antisense to 3’ UTRs and their detection using tSMS.