Table 1.
Characteristics at study entry of participants in legacy data sample.
| Demographic, Clinical and Genetic | Development cohort (n=147) | Replication cohort (n=200) |
|---|---|---|
| Mean (SD) age | 72.0 (5.6) | 73.0 (5.6) |
| Mean (SD) years of education | 14.8 (2.8) | 16.0 (2.9) |
| Female (%) | 61.2 | 54.0 |
| Non-white race (%) | 5.4 | 11.0 |
| Marital status (%) | ||
| - married | 60.5 | 61.5 |
| - widowed | 27.9 | 17.0 |
| - separated/divorced | 6.8 | 13.5 |
| - never married | 4.8 | 8.0 |
| History of hypertension (%) | 36.1 | 42.5 |
| History of diabetes (%) | 4.1 | 4.5 |
| Current or past smoking (%) | 57.5 | 56.0 |
| APOE ε4 carrier status (%) | 29.2 | 29.3 |
| Neuropsychological, in Mean (SD) | ||
| MMSE | 29.2 (1.1) | 29.2 (1.1) |
| CVLT Total Score | 50.9 (10.5) | 46.7 (12.0) |
| CVLT Percent Retention | 82.6 (18.3) | 80.8 (23.5) |
| Time to Complete Trails B | 111.3 (67.3) | 98.4 (48.9) |
| Phonemic Fluency (total of F, A, S) | 45.6 (12.3) | 43.7 (13.6) |
| Digit Span Backwards | 5.4 (1.5) | 5.2 (1.4) |
| CDR Global Rating (n [%]) | ||
| CDR = 0 | 37 (25.2) | 75 (37.5) |
| CDR = 0.5 | 110 (74.8) | 125 (62.5) |