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. Author manuscript; available in PMC: 2011 Dec 1.
Published in final edited form as: Chem Biol Drug Des. 2010 Oct 11;76(6):546–551. doi: 10.1111/j.1747-0285.2010.01035.x

Figure 2.

Figure 2

General Scheme for synthesis of mono- (16–34) and bis- (35–61) quaternary pyridinium compounds (R1 = CHNOH, CONH2; R2 = CHNOH; Position of R1 or R2: 2, 3 or 4; X = Br, Cl, OMs; R = CH2CH2Br, CH2CH2CH2Br, heterocycles – thiophene, furan or isoxazole; A = O, CH2, CH2CH2, heterocycles - thiophene-furan or isoxazole).