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. 2011 Mar 14;208(3):455–467. doi: 10.1084/jem.20101145

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© 2011 Mortensen et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).

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Figure 5. — Vav-Atg7^−/− mice are cytopenic for all blood leukocyte populations examined except CD11b⁺Gr1⁺ cells. (A–F) The absolute peripheral blood counts of TCR-β⁺ cells (A), CD19⁺ cells (B), NK1.1⁺ cells (C), CD11b⁺Gr1⁻ cells (D), CD11b⁻Gr1⁺ cells (E), and CD11b⁺Gr1⁺ cells (F) in WT (Vav-iCre⁺; Atg7^Flox/WT or Vav-iCre⁻; Atg7^Flox/Flox; n = 5) and Vav-Atg7^−/− (Vav-iCre⁺; Atg7^Flox/Flox; n = 4) mice were determined at the indicated time points between the age of 5 and 8 wk. Error bars indicate SEM (*, P < 0.05; **, P < 0.001 from Mann-Whitney tests).