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. 2011 Mar 14;208(3):593–604. doi: 10.1084/jem.20100793

Figure 4.

Figure 4.

BMCGM-CSF LTC4S is required for Df-elicited eosinophilic pulmonary inflammation. WT mice were sensitized by intranasal administration of 104 Df-pulsed WT or Ltc4s−/− BMCsGM-CSF, challenged with 2 µg Df on day 22 and day 23, and analyzed on day 25. Cells from the BAL fluid were counted, cytospin preparations were stained, and 400 cells/slide were counted for specific cell types. Results are means ± SEM (n = 13–14 mice per group) from four independent experiments. ***, P = 0.0001. Significance was determined with an unpaired Student’s t test.