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. Author manuscript; available in PMC: 2011 Mar 16.
Published in final edited form as: Nature. 2010 Feb 17;464(7286):292–296. doi: 10.1038/nature08792

Figure 1. Derivation and characterization of DKC1 mutant iPS cells.

Figure 1

a, DKC1 del37L fibroblasts and iPS colony. b, RT-PCR for endogenous ("endo") Oct4, Sox2, TERT, and Actin transcripts in del37L fibroblasts (Fib) and iPS cells derived with and without exogenous Tert. c, Histology of del37L iPS1 teratomas. d, PCR RFLP verification of del37L mutation in iPS clones. e, Telomerase activity assay in DKC1 mutant iPS lines (dash = background). f, Telomere Southern blot in DKC1 del37L fibroblasts and early passage iPS clones. g, Telomere Southern blot in DKC1 A386T fibroblasts and early passage iPS clones.