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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Nov 10;35(2):326–337. doi: 10.1111/j.1530-0277.2010.01348.x

Figure 3. Reinforcement schedule alters line difference in ethanol self-administration maintenance.

Figure 3

Comparisons of ethanol intakes during fixed ratio (FR)-4 and response requirement (RR)-8 schedules are illustrated. Each bar represents the mean ± SEM of WSP-1 (n = 16) or WSR-1 (n = 19) mice during 4 sessions on the FR4 schedule and a subsequent 2 sessions on the RR8 schedule. *P < 0.05 between selected lines for RR8 schedule; ###P < 0.001 within WSR line versus FR4 schedule; Tukey's post-hoc test.