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. 2011 Apr;25(4):1284–1294. doi: 10.1096/fj.10-160051

Figure 2.

Figure 2.

Effect of PAF inhibition on leukocyte accumulation in retinal and choroidal vessels of EIU rats. To inhibit PAF, animals were intraperitoneally treated with WEB (2.5 mg), GB (2.5 mg), or both; 30 min minutes later, EIU was induced by toepad injection of LPS (100 μg/kg), and 24 h later, animals were perfused with rhodamine-conjugated ConA to remove the intravascular content and stain vessels and firmly adhering leukocytes. A) Representative micrographs of adherent leukocytes (arrows) in retinas from control and PAF-inhibitor-treated EIU rats. Higher magnification micrographs (bottom panels) show sections of the retinal veins. B) Quantification of firmly adhering leukocytes in retinal arteries. C) Firmly adhering leukocytes in retinal veins. D) Firmly adhering leukocytes in choroidal vessels.