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. 2011 Apr;25(4):1284–1294. doi: 10.1096/fj.10-160051

Figure 6.

Figure 6.

Effect of PAF inhibitors on leukocyte and MS binding to retinal and choroidal vasculatures of normal rats. To investigate the constitutive role of PAF in endothelial function, the level of endothelial activation and leukocyte adhesion was quantified in animals 24 h after treatments. Adherent leukocytes were counted in retinal and choroidal flat mounts 24 h after intraperitoneal injection of PAF inhibitors to normal rats. A) Number of firmly adhering leukocytes in retinal arteries after GB intraperitoneal injection. B) Number of firmly adhering leukocytes in retinal veins after GB intraperitoneal injection. C) Number of bound rPSGL-1-conjugated MSs in retinal vessels after injection of WEB or GB. D) Number of bound MSs in the choroid of control animals and in those pretreated with WEB or GB.