Table III.
% Polar residuesa |
||||||||
---|---|---|---|---|---|---|---|---|
Seq. ID (%)b | % LCc | % LLLd | % VVVe | All | α | β | Coil | |
Wild-type | 100 | 3.1% | 0.063 | 0.045 | 50.1 | 51.8 | 44.7 | 52.5 |
RosettaDesign | 31.4 | 9.1% | 0.244 | 0.093 | 45.6 | 50.1 | 36.1 | 48.3 |
RosettaDesign-SR | 33.9 | 4.0% | 0.039 | 0.038 | 48.2 | 51.1 | 41.5 | 50.3 |
The results are obtained for the test set of 944 proteins with the top 1 ranked sequence in 100 sequences designed for each protein.
Frequency of polar residues for helical, strand, and coil positions, respectively.
The average sequence identity to wild type sequences of target proteins.
Percent of low-complexity regions defined by program SEG72
Percent of occurrence for three sequentially linked Leu residues.
Percent of occurrence for three sequentially linked Val residues.