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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Alcohol Clin Exp Res. 2010 Oct 6;35(1):132–139. doi: 10.1111/j.1530-0277.2010.01330.x

Figure 5. Effect of alcohol on activities of CYP2A6 and CYP3A4.

Figure 5

The activities of CYP2A6 (top panel) and CYP3A4 (bottom panel) were determined for control and alcohol-treated cells at 12 h in the absence or presence of their respective inhibitors nicotine (NIC) or ketoconazole (KTZ) as described in the Materials and Methods section. The activities, presented in Y-axis, are in percent, with 100% activity normalized for the untreated cells. 100% activity of CYP2B6 and CYP3A4 correspond to the specific activity of 93 and 46 pmoles/min/mg, respectively. * represents p≤0.05 compared to controls.