Table 1.
Met7 Contact Area in the active and inactive compounds from initial screening
Compound | Structure | Activity | Met7 Contact Area (Å2) |
---|---|---|---|
A4 | ![]() |
active | 21.6 |
B2 | ![]() |
active | 22.9 |
B6 | ![]() |
active | 22.1 |
C1 | ![]() |
active | 22.8 |
D1 | ![]() |
active | 32.6 |
E1 | ![]() |
active | 29.7 |
A1 | ![]() |
inactive | 11.1 |
A2 | ![]() |
inactive | 5.3 |
A3 | ![]() |
inactive | 2.2 |
C3 | ![]() |
inactive | 11.5 |
C6 | ![]() |
inactive | 14.7 |
D4 | ![]() |
inactive | 0 |