Table 1a.
Intact-1 | MCI-1 | AD | p | Post hoc | |
---|---|---|---|---|---|
n = 41 | n =21 | n = 27 | |||
Age, years | 79.9 ± 10.9 | 91.6 ± 6.9 | 79.7 ± 12.9 | < .0001 | MCI-1 vs. Intact-1, p < .0001 MCI-1 vs. AD, p < .0001 |
Education, years | 16.1 ± 2.2 | 15.4 ± 2.1 | 15.7 ± 2.8 | 0.56 | N/A |
Sex, % female | 56% | 43% | 59% | 0.49 | N/A |
Race, % white | 100% | 100% | 100% | 1.0 | N/A |
SES | 52.5 ± 8.5 | 49.8 ± 11.1 | 52.0 ± 10.7 | 0.58 | N/A |
MMSE* | 29.2 ± 1.0 | 26.6 ± 2.7 | 23.3 ± 2.3 | < .0001 | MCI-1 vs. Intact-1, p < .0001 MCI-1 vs. AD, p < .0001 |
CERAD Word List acquisition* | 22.5 ± 3.6 | 15.1 ± 3.3 | 12.8 ± 3.1 | < .0001 | MCI-1 vs. Intact-1, p < .0001 MCI-1 vs. AD, p = .0071 |
CERAD Word List delayed recall* | 7.8 ± 1.6 | 3.9 ± 2.0 | 1.6 ± 1.7 | < .0001 | MCI-1 vs. Intact-1, p < .0001 MCI-1 vs. AD, p < .0001 |
Age-adjusted
Note. SES = Socioeconomic status; MMSE = Mini-Mental State Examination; CERAD = Consortium to Establish a Registry for Alzheimer's Disease; Intact-1 = controls for Study 1; MCI-1 = mild cognitive impairment participants for Study 1; AD = Alzheimer's disease; N/A = Not applicable