. Author manuscript; available in PMC: 2011 May 18.

Published in final edited form as: Int J Impot Res. 2010 Nov 18;22(6):363–373. doi: 10.1038/ijir.2010.27

Table 2. Densitometric analysis of proteins involved in protein degradation in the corpora of Sickle cell mice at different life stages.

Densitometry was performed following western blot analysis of protein extracts from the corpora of sickle cell mice at three life stages (pre-priapic, priapic or late stage priapic) and age matched (non-sickle cell mice). Fold Change in expression compared to control (non-sickle cell mice) ± standard deviation. A total of six mice were used in each group (the protein extract from two animals was pooled for analysis.

Protein	Pre-Priapism	Priapism	Late Stage- Priapism
LC3-I	0.2 ± 0.18	3.85 ± 0.2 ^*	4.56 ± 0.24^*
LC3-II	0.59 ± 0.32	1.68 ± 0.5	1.11 ± 0.32
Nedd-4	22.06 ± 0.32^*	32.28 ± 0.47^*	13.06 ± 0.11^*
Mdm-2	1.24 ± 0.95	2.7 ± 1.6	1.14 ± 0.92
Bcl-2	0.3 ± 0.21	26.61 ± 0.12 ^*	39.43 ± 0.11^*

Significantly changed protein expression compared with control (Student's t-test, P < 0.05).