Table 2. FA-related lipids significantly altered by alcohol in the liver (n = 10 in each group).
Liver | Ethanol-fed mice | Pair-fed control | |||
---|---|---|---|---|---|
pmol/mg | mean | SD | mean | SD | P |
18:0 Cer | 8.1 | 1.1 | 6.0 | 1.1 | 0.0118 |
18:0/18:2 PC | 186.0 | 36.5 | 141.6 | 16.2 | 0.0375 |
18:0/18:1 PC | 128.4 | 18.8 | 97.2 | 8.6 | 0.0097 |
22:6 LPE | 3.7 | 1.1 | 1.9 | 0.5 | 0.0122 |
16:0 Cer | 27.3 | 3.7 | 21.6 | 3.2 | 0.0302 |
22:5 FA | 25.9 | 11.4 | 53.9 | 10.0 | 0.0033 |
20:4 LPA | 2.41 | 0.52 | 3.17 | 0.45 | 0.0378 |
20:4 LPC | 13.8 | 3.6 | 20.3 | 4.2 | 0.0311 |
16:0/20:4 PC | 683.3 | 50.8 | 889.6 | 79.7 | 0.0012 |
18:1 LPA | 0.29 | 0.10 | 0.44 | 0.09 | 0.0383 |
Cer: ceramide, PC: phosphatidylcholine, LPE: lysophosphatidylethanolamine, FA: fatty acid, LPA: lysophosphatidic acid, LPC: lysophosphatidylcholine