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Fig. 9. Model for regulation of bud site selection at the distal cell pole of S.cerevisiae. In YF cells, Bud9p is localized at the distal cell pole and interferes with Bud8p-mediated bud site selection via the Rsr1p/Bud1p–Bud5p–Bud2p GTPase module. In PH cells, nutritional starvation for nitrogen prevents distal localization of Bud9p, allowing efficient Bud8p-mediated distal budding.
