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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Feb 18;21(7):2030–2033. doi: 10.1016/j.bmcl.2011.02.010

Table 1.

Anthrax LF inhibitory data for LFIs represented in Figure 2.

graphic file with name nihms276917t1.jpg
LFI R3 LF (FRET) Ki(nM)
1 3 4 5 6 7 8 9
a 3-Me,4-FPh 0.05 1.5 2.4 0.39 0.62 1.3 3.0 1.2
b 4-FPh 0.24 0.58 1.2 0.13 0.81 0.93 1.1 0.25
c 4-ClPh 1.0 1.2 2.0 0.71 0.68 1.4 0.75 0.36
d CH2(4-FPh) 2.1 1.1 4.6 9.5 - - - -

Values are means of three experiments; standard deviation is < 15%; (-) = not prepared