Table 1.
LFI | R3 | LF (FRET) Ki(nM) |
|||||||
---|---|---|---|---|---|---|---|---|---|
1 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | ||
a | 3-Me,4-FPh | 0.05 | 1.5 | 2.4 | 0.39 | 0.62 | 1.3 | 3.0 | 1.2 |
b | 4-FPh | 0.24 | 0.58 | 1.2 | 0.13 | 0.81 | 0.93 | 1.1 | 0.25 |
c | 4-ClPh | 1.0 | 1.2 | 2.0 | 0.71 | 0.68 | 1.4 | 0.75 | 0.36 |
d | CH2(4-FPh) | 2.1 | 1.1 | 4.6 | 9.5 | - | - | - | - |
Values are means of three experiments; standard deviation is < 15%; (-) = not prepared