Table 2. Aberrant phenotypes in ASMko brain cells.

The table summarizes the aberrant phenotypes found until now in neurons, oligodendrocytes and astrocytes of ASMko mice brains. Corresponding references are also indicated.

Brain cell type	Aberrant phenotype	References
NEURONS
	Deficient Ca2+ homeostasis	Ginzburg and Futerman, 2005
	Altered molecular polarization	Galvan et al., 2008
	Impaired endocytosis	Galvan et al., 2008
	Smaller synapses	Camoletto et al., 2009
	Altered presynaptic plasticity	Camoletto et al., 2009
	Complete loss of Purkinje neurons	Horinouchi et al., 2005; Otterbach and Stoffel., 2005;Sarna et al., 2001; Macauley et al., 2008
	Altered lipid composition	Scandroglio et al., 2008; Galvan et al., 2008
OLIGODENDROCYTES
	Decreased expression of myelin proteins	Buccinna et al., 2009
	Altered lipid composition	Buccinna et al., 2009
ASTROCYTES
	Complete blockade of microparticle shedding and IL-1brelease	Bianco et al., 2009