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Faster pacing leads to an increase in the normalized Ca2+ transient variability, but an irregular pattern from one beat to the next. (A) Coefficient of variation (COV) in SSL Ca2+ transient amplitude, computed in a single cell as the standard deviation divided by the mean, and plotted as a function of PCL. (B) Map of SSL Ca2+ transient amplitude on the current beat versus amplitude on the next beat at several different PCLs as indicated.
