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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: J Mol Cell Cardiol. 2011 Jan 11;50(4):662–669. doi: 10.1016/j.yjmcc.2010.12.023

Figure 7.

Figure 7

An increase in triggering of Ca2+ release causes a decrease in relative Ca2+ transient variability. (A) [Ca2+] transients at two SSL regions with [Ca2+]o = 2 mM. (B) [Ca2+] transients measured from the same locations in the same cell with [Ca2+]o = 4 mM. (C) Pooled data (n=6 cells) illustrating that increasing [Ca2+]o causes a significant (p = 0.005) increase in mean SSL Ca2+ transient amplitude and a significant (p < 0.001) decrease in COV. Average COV at 4 mM is 49 ± 11% of the value at 2 mM. For these statistical comparisons, we treated the two SSL regions in each cell as independent events such that n=6 cells generated a total of n=12 data pairs for comparison.