Table 2.
Microarray gene expression results for probe sets upregulated in the setting of alcohol use disorders.
| Symbol | Description | GenBank ID | P value | Fold expression difference |
|---|---|---|---|---|
| MED28* | mediator complex subunit 28 | BF064162 | 0.000478 | 1.40 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | AW474434 | 0.000515 | 1.72 |
| SELL* | selectin L | NM_000655 | 0.000569 | 2.77 |
| GBP1 | guanylate binding protein 1, interferon-inducible, 67kDa | NM_002053 | 0.001092 | 1.57 |
| TRAM2* | translocation associated membrane protein 2 | AI986461 | 0.002274 | 1.30 |
| ASCL2 | achaete-scute complex homolog 2 (Drosophila) | AI393930 | 0.002483 | 1.50 |
| PRF1* | perforin 1 (pore forming protein) | AI445650 | 0.002721 | 3.32 |
| TRIB3 | tribbles homolog 3 (Drosophila) | NM_021158 | 0.003693 | 2.04 |
| CXCR4* | chemokine (C-X-C motif) receptor 4 | AJ224869 | 0.004592 | 1.84 |
| GCH1 | GTP cyclohydrolase 1 | NM_000161 | 0.004869 | 1.86 |
| IRF1 | interferon regulatory factor 1 | AW392551 | 0.004875 | 1.50 |
| VEGFA | vascular endothelial growth factor A | AF022375 | 0.004979 | 2.37 |
| SOD2 | superoxide dismutase 2, mitochondrial | X15132 | 0.006047 | 1.72 |
| PRF1* | perforin 1 (pore forming protein) | NM_005041 | 0.006355 | 1.99 |
| MTHFD2 | methylenetetrahydrofolate dehydrogenase (NADP+dependent) 2, methenyltetrahydrofolate cyclohydrolase | NM_006636 | 0.007039 | 1.36 |
| BIRC3 | baculoviral IAP repeat-containing 3 | U37546 | 0.007734 | 2.15 |
| IFITM2 | interferon induced transmembrane protein 2 (1–8D) | NM_006435 | 0.007963 | 1.59 |
| PDGFB* | platelet-derived growth factor beta polypeptide (simian sarcoma viral (v-sis) oncogene homolog) | AU150748 | 0.008461 | 1.43 |
| NDRG1 | N-myc downstream regulated 1 | NM_006096 | 0.00885 | 1.61 |
| GZMA | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) | NM_006144 | 0.009277 | 5.41 |
| IFITM1 | interferon induced transmembrane protein 1 (9–27) | AA749101 | 0.009562 | 4.12 |
| CD8B | CD8b molecule | NM_004931 | 0.01044 | 1.84 |
| GADD45B | growth arrest and DNA-damage-inducible, beta | AF087853 | 0.011215 | 1.54 |
| AF052160 | 0.011826 | 2.04 | ||
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | BF197357 | 0.011852 | 1.76 |
| IFITM1 | interferon induced transmembrane protein 1 (9–27) | NM_003641 | 0.01214 | 3.15 |
| RGS14 | regulator of G-protein signaling 14 | AF037195 | 0.012859 | 1.45 |
*
Probe sets that are distinctly different in the setting of AUDs, independent of smoking.