Table 5.
Gene Symbol | Test Cohort Fold Expression Difference, AUDs Subjects vs Controls | Test Cohort p Value | Confirmatory Cohort Fold Expression Difference, AUD Subjects vs Controls | Confirmatory Cohort p Value |
---|---|---|---|---|
CXCR4 | 1.77±0.14 | 0.0001 | 1.58±0.14 | 0.003 |
PRF-1 | 5.98±2.39 | 0.05 | 6.87±2.39 | 0.13 |
SELL | 3.25±0.62 | 0.01 | 2.00±0.62 | 0.04 |
MED28 | 1.02±0.10 | 0.88 | 0.94±0.10 | 0.44 |
GZMA* | 6.38±5.12 (4.50±1.43) | 0.01 (0.02) | 13.16±5.12 (6.38±1.43) | 0.31 (0.08) |
BIRC3 | 2.74±0.48 | 0.03 | 2.06±0.48 | 0.01 |
RDH10* | 0.92±1.81 (0.69±0.12) | 0.17 (0.07) | 2.82±1.81 (0.27±0.12) | 0.23 (0.20) |
Values included in parentheses exclude one outlier pair for the specified cohort.