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. Author manuscript; available in PMC: 2012 Feb 1.
Published in final edited form as: Curr Opin Genet Dev. 2010 Nov 4;21(1):86–92. doi: 10.1016/j.gde.2010.10.002

Figure 2. miRNAs in the service of p53.

Figure 2

(A) p53 induces the expression of miRNAs that target p53-repressed genes; (B) p53 induces the expression of miRNAs that enhance p53 activity output by augmenting p21 levels; (C) p53 represses miRNAs that target E2F1-induced antiproliferative genes, thereby restricting cell proliferation. See text for further details.