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. Author manuscript; available in PMC: 2012 Jan 1.
Published in final edited form as: Ann Hum Genet. 2010 Nov 30;75(1):122–132. doi: 10.1111/j.1469-1809.2010.00623.x

Figure 1.

Figure 1

Scatter plot for the values of VIMTrio and VIMAdj for the interaction term S3D ⋀ S7D, derived from the applications of trioFS to 10 simulated data sets where disease risk is determined by said interaction. The values for importance measure VIMTrio are always smaller than the corresponding values for VIMAdj, illustrating the benefit of accounting for potentially over-fitted interactions. Since SNPs were not in linkage disequilibrium, the values for the importance measure VIMLD are the same as the ones for VIMTrio, and are omitted from the plot.