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. Author manuscript; available in PMC: 2012 Mar 22.
Published in final edited form as: Biochemistry. 2011 Feb 15;50(11):1885–1893. doi: 10.1021/bi101921w

Figure 5.

Figure 5

Ap4A interactions with the side chain of Arg131 and corresponding Fo−Fc omit electron density (gray) contoured at 2.5σ. Strong electron density is observed for all three Ap4A molecules bound to AgAK. A: First AgAK molecule where electron density is clearly shown at the side chain of Arg131. The side chain of Arg131 hydrogen bonds to the phosphate from AMP moiety and is in proximity to the backbone of Asn296. Distances shorter than 3.2 Å are indicated as black dash lines. B: Second AgAK molecule, the electron density of the guanidine group of Arg131 is missing. C: Third AgAK molecule, the electron density of the side chain of Arg131 is almost absent but strong density of the backbone of the residues 288 to 295 is observed. The 2Fo−Fc electron density map (at 1σ) from Val293 to Asn296 is colored in blue.